2Assistant Dr. ,Ulucanlar Training and Research Hospital, Ophthalmology Department, Ankara, Turkey
3Prof. Dr. MD,Ulucanlar Training and Research Hospital, Ophthalmology Department, Ankara, Turkey DOI : 10.37844/glauc.cat.2021.16.16 Purpose: In this study, our aim was to investigate the acute effects of captopril on intraocular pressure (IOP) in patients who received captopril preoperatively due to high systemic arterial blood pressure (SABP) before cataract surgery.
Material and Methods: This prospective and cross-sectional study included 28 eyes of 28 patients, who presented for cataract surgery and preoperatively received captopril (25 mg, sublingual) due to detection of high SABP between December, 2019 and April, 2020. The IOP and anterior chamber depth (ACD) measurements were performed by Goldmann applanation tonometry and ocular biometry (Lenstar LS 900, Haag-Streit, USA) immediately before and 30 minutes after the drug intake. Wilcoxon test was used for statistical analysis.
Results: The study included 28 patients (18 female, 10 male) mean age was 64.9±10.7 (49-85). Signifi cant decreases were observed in systolic blood pressure and mean arterial blood pressure after the drug intake (P?0.001 and P=0.001, respectively). No signifi cant difference was found in diastolic blood pressure, ACD, and IOP parameters (P>0.05 for all).
Conclusion: This study concluded that the preoperative usage of captopril to lower the SABP in cataract cases had no acute effects on IOP; thus it can be safely used before the operation.
Keywords : Captopril, Cataract Surgery, Hypertension, Intraocular pressure