2Doç. Dr., S.B. Ulucanlar Göz Eğitim Hastanesi, Göz Kliniği, Ankara, Türkiye
3Uz. Dr., S.B. Ulucanlar Göz Eğitim Hastanesi, Göz Kliniği, Ankara, Türkiye Purpose: Our aim was to compare the outcomes of initial trabeculectomy and Ex-Press miniature implant with mitomycin C (mit C) and preoperative intravitreal bevacizumab injection in the management of neovascular glaucoma (NVG).
Material and Methods: This retrospective study consisted of 11 eyes with NVG those underwent initial trabeculectomy with mit C and 9 eyes with NVG those underwent Ex-Press miniature implant with mit C. Preoperatively panretinal photocoagulation had been performed and intravitreal bevacizumab (1.25 mg/0.05 mL) had been injected 10 days before the surgery for all eyes. The intraocular pressure (IOP) and the number of antiglaucomatous medications were compared at the fi rst week, fi rst month, third month, sixth month and first year after the surgery. Independent t, Kolmogorov-Smirnov and chi square tests were used for statistical analysis.
Results: In trabeculectomy group preoperative IOP was 39.4±3.6 mmHg and postoperative values were 10.4±2.3 mmHg (1st week), 11.4±1.9 mmHg (1st month), 15.2±2.04 mmHg (3rd month), 16.7±2.6 mmHg (6th month) and 18.9±3.6 mmHg (1st year). In Ex-Press group preoperative IOP was 38.4±5.8 mmHg and postoperative values were 10.3±2.1 mmHg (1st week), 11.5±2.3 mmHg (1st month), 15.4±1.8 mmHg (3rd month), 18.3±2.9 mmHg (6th month) and 18.2±3.9 mmHg (1st year). In both groups IOP and the number of medications reduced signifi cantly postoperatively. There were no signifi cant differences between the preoperative and the postoperative IOP values of the two groups.
Conclusion: Both mit C-augmented trabeculectomy and mit C-augmented Ex-Press implant provided similar reduction of IOP in cases with NVG in 1 year follow-up period.
Keywords : Neovascular glaucoma, trabeculectomy, mitomycin C, Ex-Press miniature implant