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¹Uz. Dr., İzmir Bozyaka Eğitim Arastırma Hastanesi, Göz Hastalıkları, İzmir, Türkiye
²Asist. Dr., İzmir Bozyaka Eğitim Arastırma Hastanesi, Göz Hastalıkları, İzmir, Türkiye
³Doç. Dr., İzmir Bozyaka Eğitim Arastırma Hastanesi, Göz Hastalıkları, İzmir, Türkiye A 43-year-old female patient presented with headache, vomiting episode, blurring of vision, and photophobia. Patient had no prior history of glaucoma and/or any other ocular abnormalities but had a history of migraine and was started with topiramate acetate 2 days prior to admission. Slit lamp examination revealed conjunctival hyperemia, chemosis and shallow anterior chambers. Intraocular pressure was measured as 40 mm Hg in both eyes. Fundoscopic examination findings were normal. Ultrasound scan was performed and demonstrated separation between the choroidal layer and the sclera. A diagnosis of bilateral uveal effusion associated with the use of oral topiramate was made. Patient?s symptoms responded well to topiramate discontinuation, topical and systemic anti glaucomatous medications and topical cycloplegic agents. In the follow-up period, visual acuity, intraocular pressure, gonioscopic and anterior segment optical coherence tomography findings returned to normal. Bilateral acute angle closure may develop after ingestion of topiramate. So, the possibility of bilateral acute angle closure glaucoma must be kept in mind in adult and elderly subjects with headache and blurred vision after the use of topiramate. Due to the possible ophthalmic side effect, patients should be informed and warned before topiramate intake. This side effect is rare but can lead to irreversible vision loss if it is not recognized in time and if it is not managed immediately by an ophthalmologist. Keywords : angle closure glaucoma, anterior segment optical coherence tomography, gonioscopy, topiramate, uveal effusion