Materials and Methods: We retrospectively reviewed patients with non-persistent pseudophakic cystoid macular edema who responded to topical therapy plus follow-up within 3 months between January 2018 and October 2020. Age, gender, anterior and posterior segment findings, intraocular pressures, refractive errors and axial lengths of the patients were recorded. Macular layers, volumes and ganglion cell analysis were examined by optical coherence tomography. The distance between the inner limiting membrane and the outer limiting membrane was measured in the inner retinal layer, and it was recorded as M1.

Results: The mean age was 71.33±7.12 in the patients included. Baseline visual acuity was 0.48±0.23 in logMAR in the patient group, while final visual acuity was 0.1±0.096 in logMAR. Average recovery time was 2 months (1-3 months). When the patient and healthy eyes were compared, significant thinning was found in 9 quadrants according to the ETDRS, inner retinal layer (M1), foveal thickness. A strong positive correlation was found between post-treatment vision levels and M1 measurements of eyes with PCME. (p= 0.000)

Conclusion: It should be kept in mind that even if vision is restored in non-resistant cystoid macular edema, it may cause atrophy in the retinal layers. Keywords : Optical coherence tomography, pseudophakic cystoid macular edema, retinal atrophy