Material and methods: Thirteen eyes of eight patients with clinically diagnosed PCG were enrolled and compared with twenty control corneas in Kocaeli University Medical Faculty Ophthalmology Clinic Glaucoma Department. Clinical parameters; best corrected visual acuity (BCVA), central corneal thickness (CCT), anterior chamber diameter (ACD), corneal diameter (WTW), axial length (Ax) and IVKM parameters; the cell density of basal epithelium, keratocytes and endothelium were compared with control corneas. The scarred corneas were excluded.

Results: CCT was measured as 547.29 ± 51.93?m in the PCG group, 562.65 ± 28.55?m in the control group (p=0.301) and ACD was measured as 4.14 ± 0.74 mm in the PCG group and 3.43 ± 0.27mm in the control group (p = 0.005). There was statisticaly signifi cant difference between groups in terms of WTW (p<0.001). Basal epithelial cell density was 5582±488 cell/mm2 in PCG group and 6249±531 cell/mm2 in control group (p=0.003). There were statistically signifi cant difference in terms of posterior keratocytes and endothelial cell densities between PCG (338±82 cell/mm2, 2203±630 cell/mm2, respectively) and control groups (6249±531 cell/mm2, 3317±551 cell/mm2, respectively), (p=0.042, p<0.001, respectively). There was no signifi cant change in anterior keratocyte cell density (p=0.803). Stromal nerve fi brils were observed in the abnormal morphological structure. Endothelial cell pleomorphism was notable in some buphthalmic eyes.

Conclusion: This diminished density in the corneal layers and pleomorphism in endothelial cells should be kept in mind following the patients and before the surgical decision. Keywords : Confocal microscopy, congenital glaucoma