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Dokuz Eylul University Faculty of Medicine, Department of Ophthalmology, Izmir/TURKEY While glaucoma is the most common cause of optic disc cupping, it can also be seen in congenital, traumatic, toxic, ischemic, inflammatory and compressive optic neuropathies. Previous studies indicated that ~20% of patients were misdiagnosed with glaucoma. Hereby, we describe the clinical and morphological properties of glaucomatous and nonglaucomatous optic disc neuropathies and how to make diffirential diagnosis. Keywords : Glaucoma, Morning Glory syndrome, optic nerve