2M.D. Asistant, Ulucanlar Training and Reseach Eye Hospital, Ankara/TURKEY
3M.D., Gazi Mustafa Kemal State Hospital, Eye Clinic, Ankara/TURKEY
4M.D., Ulucanlar Training and Reseach Eye Hospital, Ankara/TURKEY Purpose: To compare corneal biomechanical properties changes in normal subjects with aging and evaluate its effect on intraocular pressure (IOP).
Material and Methods: Group 1 was composed of 46 eyes of 23 subjects who were under 50 years old and group 2 was composed of 54 eyes of 27 subjects who were equal or above 50 years old. Corneal biomechanical properties were measured with Ocular Response Analyzer (ORA). Corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated intraocular pressure (IOPcc) and Goldmann-correlated intraocular pressure (IOPg) were obtained from ORA were evaluated as corneal biomechanical properties.
Results: Mean CH levels were 10.1±2.1 (3.5-13.1) and 9.1±1.2 (7.6-13.0) mmHg in Group 1 and Group 2, respectively. The mean CH levels were significantly lower in Group 2 (p=0.01).The mean CRF levels were 10.5±2.2 (4.8-13.9) and 9.2±1.3 (6.8-12.2) mmHg in Group 1 and Group 2, respectively. The mean CRF levels were significantly higher in Group 1 (subjects below 50 years old) (p=0.004). Mean IOPg levels were 16.6 ±4.1 (9-25.9) mmHg in Group 1 and 15.2 ±3.1 (8.8-20.4) mmHg in Group 2 and mean IOPcc levels were 17.3±4.2 (12-25.5) mmHg in Group 1 and 17±3.1 (11.5-22.6) mmHg in Group 2. The mean IOPcc and IOPg levels were not significantly different between groups (p>0.05).
Conclusion: According to our results corneal biomechanical properties were changed with aging process and IOP measurements were also affected by corneal biomechanical properties related to aging process and IOP values obtained from GAT were lower than IOP values of ORA results.
Keywords : Intraocular pressure, cornea hysteresis, cornea resistance factor, ocular response analyzer