Material and Methods: We assessed retrospectively 11 eyes of the 8 OAG patients whom had been operated with uncomplicated phacoemulsification surgery previously, and have high IOP despite maximal tolerable medication and then operated with ex-press shunt surgery with 5-Fluorouracil.

Results: Cases are followed on average 15.3±7.5 (6-26) months after the surgery. Mean IOP (intraocular pressure) of 11 eyes was detected as 27.9+-3.2(24-34) mmHg pre-operatively and reduced to 13.6+/-2.2 (11-18) mm Hg post-operatively at the last control. Decrease in the IOP was statistically significant (p<0.05). Average number of pre-operative medications was 2.63±0.5 and none of the cases needed medical treatment post-operatively. We did not have any complication except cystic bleb occurrence in one patient. No significant change was recorded in visual acuity and c/d ratios.

Conclusions: Although we have limited number of cases, Ex-press implantation with 5-Fluororuracil was found quite effective and safe in control of IOP in pseudophacic OAG patients. Few studies are present about Ex-press implantation in these pseudophacic patients and we think that firstly usage of 5-Fluorouracil will provide additional contribution to literature. Keywords : Glaucoma, intraocular pressure, Ex-press glaucoma shunt, pseudophacy, 5-Fluorouracil