Materials and Methods: Data belonging to 71 eyes diagnosed as glaucoma of 38 patients, 21 women 17 men, were evaluated. These data retrospectively were obtained from hospital records. Those patients admitted to glaucoma clinic between 2002-2005 years were treated with latanoprost %0.005 or carteolol %2 monotherapy. Duration of drugs as alone and its efficacy on C/D ratio progression and initial intraocular pressure were evaluated, as classifying the patients according to having types of glaucoma, kinds of monodrugs admitted, age and sex.

Results: 28, 16, 14, 9, 2, 2 of 71 eyes with glaucoma were diagnosed as normal pressure glaucoma, primary open angle, ocular hypertension, pseudoexfoliative, pigmentary, and closed angle glaucoma respectively. Latanoprost 0.005% to 23 eyes of 71, carteolol 2% to 48 were admitted topically. The ratio of drugs sufficiency when used alone for first 6 months and 12 months were 100%-73.9% for latanoprost group, 72.91%-52.08% for carteolol group were obtained. Although in both two groups, statistically significant low IOP was obtained, there was no statistically significant difference between two groups for C/D ratio progression during first year follow-up.

Conclusion: The efficacy of latanoprost 0.005% and carteolol 2% in maintaining the level of their IOP control were found similar, but the duration and rate of target intraocular pressure with latanoprost 0.005% was superior to carteolol 2% when compared them by using monotherapy during first year follow-up. Keywords : Blindness, carteolol, glaucoma, latanoprost, treatment