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¹Üsküdar Devlet Hastanesi, Göz Hastalıkları, İstanbul, Uz. Dr.
²GATA Haydarpaşa Eğitim Hastanesi, Göz Hastalıkları, İstanbul, Yrd. Doç. Dr. Purpose: To evaluate the efficiency of brimonidin 0.2%on an intraocular pressure (IOP) increase after Nd:YAG laser posterior capsulotomy.
Materials and Methods: Eighty patients (88 eyes) who had posterior capsule opacification after phacoemulsification and posterior chamber IOL implantation surgery were included. Patients’ visual acuity and IOP were measured, and a biomicroscopic examination was performed before capsulotomy. Before the laser surgery apraclonidine 0.5%was applied in all patients. Brimonidin 0.2%was applied twice daily in the first group (42 eyes) after capsulotomy. The other group was the control group (46 eyes); it received no antiglaucomatous treatment. IOP values were measured after 1 hour, 1 day, 1 week, and 1 month.
Results: Mean age was 63.1±23.12. The time from cataract surgery to posterior capsulotomy was a mean of 22±9.3 (2-48) months. Before capsulotomy, while the mean IOP was 15.2±3.7 mmHg in the first group, it was 16.1±2.2 after 1 hour, 16.1±2.4 after 1 day, 15.7±3.2 after 1 week, and 14.1±2.2 after 1 month. In the control group it was 14.7±3.2 mmHg before the procedure, while it was 17.7±3.4 after 1 hour, 18.2±2.7 after 1 day, 16.2±3.4 after 1 week, and 15.2±2.8 after 1 month. Statistical significance was determined between mean IOP measurements in the two groups (p<0.05). Moreover, no significant IOP increase was seen in the brimonidine group compared to before surgery (p>0.05). In the control group the IOP increase was statistically significant after 1 hour and 1 day (p<0.05).
Conclusion: Topical use of brimonidine 0.2%for 1 week after Nd:YAG laser posterior capsulotomy is effective in preventing IOP elevation in the early period. Keywords : Nd:YAG laser, posterior capsulotomy, intraocular pressure, brimonidine